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Roflumilast Oral tablet

What is this medicine?

ROFLUMILAST (roe FLUE mi last) decreases inflammation in the lungs. This medicine is used to prevent COPD flare-ups. Do not use this medicine to treat sudden breathing problems.

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You can take it with or without food. If it upsets your stomach, take it with food. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you've taken too much of this medicine contact a poison control center or emergency room at once.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • anxious

  • breathing problems

  • suicidal thoughts or other mood changes

  • trouble sleeping

  • weight loss

Side effects that usually do not require medical attention (Report these to your doctor or health care professional if they continue or are bothersome.):

  • back pain

  • diarrhea

  • dizziness

  • general ill feeling or flu-like symptoms

  • headache

  • loss of appetite

  • nausea, vomiting

What may interact with this medicine?

  • carbamazepine

  • cimetidine

  • enoxacin

  • erythromycin

  • fluvoxamine

  • ketoconazole

  • phenobarbital

  • phenytoin

  • rifampicin

  • St. John's wort

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • liver disease

  • mental illness

  • an unusual or allergic reaction to roflumilast, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Visit your doctor for regular check ups. Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

Online Medical Reviewer: Louise Akin, RN, BSN
Online Medical Reviewer: Daphne Pierce-Smith, RN, MSN, FNP, CCRC
Date Last Reviewed: 11/8/2013
© 2000-2014 The StayWell Company, LLC. 780 Township Line Road, Yardley, PA 19067. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.
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